ncRNA name | FABP5 siRNA |
ncRNA Category | siRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | siRNA transfection,qRT-PCR, Western blot, Fatty acid uptake assay, Nile Red staining, Electrospray tandem mass spectrometry, immunoprecipitation |
Expression pattern | associated |
Functional description | FABP5 downregulation in the RPE/choroid complex in vivo might contribute to aging and early age-related macular degeneration. |
PubMed ID | 19434059 |
Year | 2010 |
Title | Knockdown of FABP5 mRNA decreases cellular cholesterol levels and results in decreased apoB100 secretion and triglyceride accumulation in ARPE-19 cells. |
Drug-related ncRNA | NO |
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